Research Article Open Access

Toxicity studies of agrochemicals to adults of frog Rana tigrina using pharmacological bioassays

Abstract

The wide scale use of agrochemicals and their hazardous impact on biotic components of aquatic and terrestrial ecosystems has been the subject of debate since last two years. Recently many workers have reported toxicity of metals and agrochemicals to frog. Present study was aimed to determine the acute toxicity of different groups of pesticides to the adults of Indian bullfrog Rana tigrina. Isolated rectus abdominus preparation was used for the evaluation of toxicity to the skeletal tissues. While cardiac toxicity was determined by using isolated heart perfusion technique. Acute toxicity of three agrochemicals, one herbicide Paraquat and two fungicides Indofil and Fytolan was estimated to the adults of frog Rana tigrina. Among these bipyridium herbicide was found to be highly toxic followed by carbamate fungicide indofil and copper based fungicide fytolan.

A. R. CHOPADE, N. S. NAIKWADE, A. Y. NALAWADE, V. B. SHINDE and K. B. BURADE

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